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  • Complement Inhibitor class drugs

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    8 results
    • bkemv

      (eculizumab-aeeb)
      Amgen Inc
      Usage: BKEMV is indicated for treating paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis, atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy, and generalized myasthenia gravis (gMG) in adults who are anti-acetylcholine receptor (AchR) antibody positive. It is not for Shiga toxin E. coli related HUS.
    • empaveli

      (Pegcetacoplan)
      Apellis Pharmaceuticals, Inc.
      Usage: EMPAVELI® is indicated for treating adult patients with paroxysmal nocturnal hemoglobinuria (PNH).
    • epysqli

      (Eculizumab-aagh)
      Teva Pharmaceuticals USA, Inc.
      Usage: EPYSQLI is indicated for treating paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis, atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy, and generalized myasthenia gravis (gMG) in adults who are anti-acetylcholine receptor (AchR) antibody positive. Not for STEC-HUS.
    • izervay

      (avacincaptad pegol)
      Astellas Pharma US, Inc.
      Usage: IZERVAY™ is indicated for the treatment of geographic atrophy (GA) associated with age-related macular degeneration (AMD).
    • soliris

      (ECULIZUMAB)
      Alexion Pharmaceuticals Inc.
      Usage: SOLIRIS is indicated for treating paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia gravis (gMG) in patients six years or older who are anti-AChR antibody positive, and neuromyelitis optica spectrum disorder (NMOSD) in anti-AQP4 antibody positive adults.
    • syfovre

      (Pegcetacoplan)
      Apellis Pharmaceuticals, Inc.
      Usage: SYFOVRE is indicated for the treatment of geographic atrophy (GA) due to age-related macular degeneration (AMD).
    • ultomiris

      (ravulizumab)
      Alexion Pharmaceuticals Inc.
      Usage: ULTOMIRIS is indicated for treating paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS) in patients aged one month and older, generalized myasthenia gravis (gMG) in AChR antibody-positive adults, and neuromyelitis optica spectrum disorder (NMOSD) in AQP4 antibody-positive adults.
    • veopoz

      (Pozelimab)
      Regeneron Pharmaceuticals, Inc.
      Usage: VEOPOZ is indicated for treating adult and pediatric patients aged 1 year and older with CD55-deficient protein-losing enteropathy (PLE), also referred to as CHAPLE disease.