Complement Inhibitors [MoA] class drugs

8 results

  • bkemv - eculizumab - aeeb injection, solution, concentrate

    (Eculizumab-Aeeb)
    Amgen Inc
    Bkemv is a complement inhibitor used to treat: paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis; atypical hemolytic uremic syndrome (aHUS) to block clot-forming damage; generalized myasthenia gravis (AChR antibody-positive adults); and neuromyelitis optica spectrum disorder (AQP4 antibody-positive adults). Not for STEC-HUS.
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    Drug Interactions

  • empaveli - pegcetacoplan injection, solution

    (Pegcetacoplan)
    Apellis Pharmaceuticals, Inc.
    Empaveli is a complement inhibitor for adults with paroxysmal nocturnal hemoglobinuria (PNH), and for adults and patients aged 12 and older with C3 glomerulopathy (C3G) or primary immune-complex membranoproliferative glomerulonephritis (IC-MPGN) to reduce proteinuria.
    Medication Details
    Drug Interactions

  • soliris - eculizumab injection, solution, concentrate

    (Eculizumab)
    Alexion Pharmaceuticals Inc.
    Soliris treats paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia gravis (gMG) in AChR antibody-positive patients aged 6 and older, and neuromyelitis optica spectrum disorder (NMOSD) in AQP4 antibody-positive adults. Not indicated for STEC-HUS.
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    Drug Interactions

  • ultomiris - ravulizumab solution, concentrate

    (Ravulizumab)
    Alexion Pharmaceuticals Inc.
    Ultomiris treats PNH and aHUS (including complement-mediated TMA) in adults and pediatric patients one month and older. Also indicated for AChR antibody-positive generalized myasthenia gravis and AQP4 antibody-positive neuromyelitis optica spectrum disorder in adults. Not for STEC-HUS.
    Medication Details
    Drug Interactions