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    • HER2/neu Receptor Antagonist class drugs

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    9 results

    • enhertu

      (fam-trastuzumab deruxtecan-nxki)
      Daiichi Sankyo Inc.
      Usage: ENHERTU is indicated for treating adult patients with unresectable or metastatic HER2-positive breast cancer, HER2-low or HER2-ultralow breast cancer, HER2-mutant non-small cell lung cancer, advanced HER2-positive gastric cancer, and unresectable HER2-positive solid tumors, all following prior systemic therapies.

    • herceptin

      (Trastuzumab)
      Genentech, Inc.
      Usage: Herceptin is indicated for the adjuvant treatment of HER2-overexpressing breast cancer, metastatic breast cancer in combination with paclitaxel, or as a single agent after previous regimens. It is also used with cisplatin and capecitabine for HER2-positive metastatic gastric cancer. Patient selection should utilize an FDA-approved diagnostic.

    • herceptin hylecta

      (Trastuzumab and hyaluronidase-oysk)
      Genentech, Inc.
      Usage: HERCEPTIN HYLECTA is indicated for adjuvant treatment of HER2 overexpressing breast cancer in adults, either as part of a combination regimen with specific chemotherapy agents or as a single agent after anthracycline-based therapy. It is also used for first-line and subsequent treatment of metastatic breast cancer.

    • herzuma

      (TRASTUZUMAB)
      Cephalon, Inc.
      Usage: HERZUMA is indicated for adults with HER2 overexpressing breast cancer, both in adjuvant and metastatic settings, and for metastatic gastric or gastroesophageal junction adenocarcinoma. Treatment modalities include combinations with specific chemotherapies or as a single agent, guided by FDA-approved diagnostics.

    • kadcyla

      (ADO-TRASTUZUMAB EMTANSINE)
      Genentech, Inc.
      Usage: KADCYLA is indicated for treating HER2-positive metastatic breast cancer in patients who have previously received trastuzumab and a taxane, or for early breast cancer in those with residual disease after neoadjuvant therapy. Patient selection should use an FDA-approved companion diagnostic.

    • margenza

      (margetuximab-cmkb)
      MacroGenics, Inc
      Usage: MARGENZA is indicated for treating adult patients with metastatic HER2-positive breast cancer, in combination with chemotherapy, who have previously received two or more anti-HER2 regimens, including one for metastatic disease.

    • perjeta

      (Pertuzumab)
      Genentech, Inc.
      Usage: PERJETA is indicated for treating adults with HER2-positive metastatic breast cancer in combination with trastuzumab and docetaxel, as well as for neoadjuvant and adjuvant treatment of HER2-positive early breast cancer at high risk of recurrence, in combination with trastuzumab and chemotherapy.

    • phesgo

      (pertuzumab, trastuzumab, and hyaluronidase-zzxf)
      Genentech, Inc.
      Usage: PHESGO is indicated for combination with chemotherapy in adults with HER2-positive early breast cancer for neoadjuvant and adjuvant treatment, and for those with HER2-positive metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy. Patient selection is based on an FDA-approved diagnostic test.

    • trazimera

      (trastuzumab-qyyp)
      Pfizer Laboratories Div Pfizer Inc
      Usage: TRAZIMERA is indicated for adjuvant treatment of HER2-overexpressing breast cancer (both node-positive and node-negative) and for metastatic breast cancer (in combination with paclitaxel or as a single agent). It is also indicated for HER2-overexpressing metastatic gastric cancer, used with cisplatin and capecitabine or 5-fluorouracil.