Caplyta Drug Interactions: 165 Major, 320 Moderate
Caplyta (Lumateperone) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Caplyta. Always confirm against the full prescribing information.
100 interactions
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Lumateperone.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Alfentanil is combined with Lumateperone.
Level 2 evidence
Almotriptan
The risk or severity of adverse effects can be increased when Almotriptan is combined with Lumateperone.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Alosetron is combined with Lumateperone.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Lumateperone.
Level 2 evidence
Amantadine
The therapeutic efficacy of Amantadine can be decreased when used in combination with Lumateperone.
Level 2 evidence
Amiodarone
The serum concentration of Lumateperone can be increased when it is combined with Amiodarone.
Level 1 evidence
Amoxapine
The risk or severity of adverse effects can be increased when Amoxapine is combined with Lumateperone.
Level 2 evidence
Amphetamine
Lumateperone may decrease the stimulatory activities of Amphetamine.
Level 2 evidence
Apomorphine
The therapeutic efficacy of Apomorphine can be decreased when used in combination with Lumateperone.
Level 2 evidence
Aprepitant
The serum concentration of Lumateperone can be increased when it is combined with Aprepitant.
Level 1 evidence
Aripiprazole
The risk or severity of adverse effects can be increased when Lumateperone is combined with Aripiprazole.
Level 2 evidence
Enter your NPI to unlock 36 major interactions for Caplyta
Caplyta (Lumateperone) has 497 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Caplyta (Lumateperone) has 165 major, 320 moderate, and 12 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Caplyta. Always confirm against the full prescribing information.