0 interactions for Combipatch (Estradiol/Norethindrone Acetate Transdermal System)- Estradiol/Norethindrone Acetate Transdermal System patch, Extended Release®A therapy excluded from this list of known interactions does not necessarily mean that no interactions exist between that therapy and and Combipatch (Estradiol/Norethindrone Acetate Transdermal System)- Estradiol/Norethindrone Acetate Transdermal System patch, Extended Release®.