Harvoni (Ledipasvir And Sofosbuvir) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Harvoni. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
Abemaciclib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Abrocitinib
The serum concentration of Ledipasvir can be increased when it is combined with Abrocitinib.
Level 1 evidence
Abrocitinib
The serum concentration of Sofosbuvir can be increased when it is combined with Abrocitinib.
Level 2 evidence
Adagrasib
The serum concentration of Ledipasvir can be increased when it is combined with Adagrasib.
Level 1 evidence
Adagrasib
The serum concentration of Sofosbuvir can be increased when it is combined with Adagrasib.
Level 2 evidence
Adenovirus type 7 vaccine live
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Sofosbuvir.
Level 2 evidence
Adenovirus type 7 vaccine live
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Ledipasvir.
Level 2 evidence
Afatinib
The serum concentration of Ledipasvir can be increased when it is combined with Afatinib.
Level 1 evidence
Afatinib
Afatinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Allopurinol
Ledipasvir may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Level 2 evidence
Almasilate
Almasilate can cause a decrease in the absorption of Ledipasvir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Enter your NPI to unlock 3 major interactions for Harvoni
Harvoni (Ledipasvir And Sofosbuvir) has 1474 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Harvoni (Ledipasvir And Sofosbuvir) has 53 major, 550 moderate, and 871 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Harvoni. Always confirm against the full prescribing information.