Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Horizant. Always confirm against the full prescribing information.
100 interactions
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Gabapentin enacarbil.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Alfentanil is combined with Gabapentin enacarbil.
Level 2 evidence
Almasilate
The serum concentration of Gabapentin enacarbil can be decreased when it is combined with Almasilate.
Level 1 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Almotriptan is combined with Gabapentin enacarbil.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Alosetron is combined with Gabapentin enacarbil.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Gabapentin enacarbil.
Level 2 evidence
Aluminium phosphate
The serum concentration of Gabapentin enacarbil can be decreased when it is combined with Aluminium phosphate.
Level 1 evidence
Aluminum hydroxide
The serum concentration of Gabapentin enacarbil can be decreased when it is combined with Aluminum hydroxide.
Level 1 evidence
Amikacin
Gabapentin enacarbil may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amisulpride
The risk or severity of CNS depression can be increased when Amisulpride is combined with Gabapentin enacarbil.
Level 2 evidence
Amitriptyline
The risk or severity of CNS depression can be increased when Amitriptyline is combined with Gabapentin enacarbil.
Level 2 evidence
Amobarbital
The risk or severity of CNS depression can be increased when Amobarbital is combined with Gabapentin enacarbil.
Level 2 evidence
Enter your NPI to unlock 1 major interaction for Horizant
Horizant (Gabapentin Enacarbil) has 694 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Horizant (Gabapentin Enacarbil) has 7 major, 284 moderate, and 403 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Horizant. Always confirm against the full prescribing information.