Mektovi Drug Interactions: 276 Major, 210 Moderate
Mektovi (Binimetinib) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Mektovi. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
Abemaciclib may decrease the excretion rate of Binimetinib which could result in a higher serum level.
Level 2 evidence
Acetaminophen
The metabolism of Binimetinib can be decreased when combined with Acetaminophen.
Level 2 evidence
Acyclovir
The metabolism of Binimetinib can be decreased when combined with Acyclovir.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Binimetinib which could result in a higher serum level.
Level 2 evidence
Ambrisentan
The serum concentration of Binimetinib can be increased when it is combined with Ambrisentan.
Level 2 evidence
Antipyrine
The metabolism of Binimetinib can be decreased when combined with Antipyrine.
Level 2 evidence
Apalutamide
The serum concentration of Binimetinib can be decreased when it is combined with Apalutamide.
Level 1 evidence
Apixaban
The serum concentration of Binimetinib can be increased when it is combined with Apixaban.
Level 2 evidence
Articaine
The risk or severity of methemoglobinemia can be increased when Binimetinib is combined with Articaine.
Level 1 evidence
Asciminib
The serum concentration of Binimetinib can be increased when it is combined with Asciminib.
Level 1 evidence
Asenapine
The metabolism of Binimetinib can be decreased when combined with Asenapine.
Level 2 evidence
Avanafil
Avanafil may decrease the excretion rate of Binimetinib which could result in a higher serum level.
Level 2 evidence
Enter your NPI to unlock 52 major interactions for Mektovi
Mektovi (Binimetinib) has 506 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Mektovi (Binimetinib) has 276 major, 210 moderate, and 20 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Mektovi. Always confirm against the full prescribing information.