Methylphenidate Extended-Release Drug Interactions: 17 Major
Methylphenidate Extended-Release Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methylphenidate Extended-Release. Always confirm against the full prescribing information.
100 interactions
Acenocoumarol
The metabolism of Acenocoumarol can be decreased when combined with Methylphenidate.
Level 1 evidence
Acetazolamide
The therapeutic efficacy of Acetazolamide can be decreased when used in combination with Methylphenidate.
Level 2 evidence
Almasilate
Almasilate can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Aluminium phosphate
Aluminium phosphate can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Aluminum hydroxide
Aluminum hydroxide can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Amantadine
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Amantadine.
Level 2 evidence
Amifampridine
The risk or severity of seizure can be increased when Methylphenidate is combined with Amifampridine.
Level 2 evidence
Amisulpride
The risk or severity of adverse effects can be increased when Amisulpride is combined with Methylphenidate.
Level 2 evidence
Amitriptyline
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Amitriptyline.
Level 2 evidence
Amobarbital
The therapeutic efficacy of Amobarbital can be decreased when used in combination with Methylphenidate.
Level 2 evidence
Amoxapine
The risk or severity of adverse effects can be increased when Amoxapine is combined with Methylphenidate.
Level 2 evidence
Apomorphine
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Apomorphine.
Methylphenidate Extended-Release has 700 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Methylphenidate Extended-Release has 17 major, 126 moderate, and 557 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methylphenidate Extended-Release. Always confirm against the full prescribing information.