Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methylphenidate Hcl. Always confirm against the full prescribing information.
100 interactions
Acenocoumarol
The metabolism of Acenocoumarol can be decreased when combined with Methylphenidate.
Level 1 evidence
Acetazolamide
The therapeutic efficacy of Acetazolamide can be decreased when used in combination with Methylphenidate.
Level 2 evidence
Almasilate
Almasilate can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Aluminium phosphate
Aluminium phosphate can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Aluminum hydroxide
Aluminum hydroxide can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Level 2 evidence
Amantadine
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Amantadine.
Level 2 evidence
Amifampridine
The risk or severity of seizure can be increased when Methylphenidate is combined with Amifampridine.
Level 2 evidence
Amisulpride
The risk or severity of adverse effects can be increased when Amisulpride is combined with Methylphenidate.
Level 2 evidence
Amitriptyline
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Amitriptyline.
Level 2 evidence
Amobarbital
The therapeutic efficacy of Amobarbital can be decreased when used in combination with Methylphenidate.
Level 2 evidence
Amoxapine
The risk or severity of adverse effects can be increased when Amoxapine is combined with Methylphenidate.
Level 2 evidence
Apomorphine
The risk or severity of adverse effects can be increased when Methylphenidate is combined with Apomorphine.
Methylphenidate Hcl has 700 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Methylphenidate Hcl has 17 major, 126 moderate, and 557 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methylphenidate Hcl. Always confirm against the full prescribing information.