Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Skyla. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Levonorgestrel can be increased when combined with Abatacept.
Level 1 evidence
Acarbose
The therapeutic efficacy of Acarbose can be decreased when used in combination with Levonorgestrel.
Level 2 evidence
Acenocoumarol
The risk or severity of adverse effects can be increased when Levonorgestrel is combined with Acenocoumarol.
Level 1 evidence
Acetaminophen
The metabolism of Levonorgestrel can be increased when combined with Acetaminophen.
Level 2 evidence
Acetazolamide
The metabolism of Levonorgestrel can be increased when combined with Acetazolamide.
Level 1 evidence
Acitretin
The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Acitretin.
Level 1 evidence
Adalimumab
The metabolism of Levonorgestrel can be increased when combined with Adalimumab.
Level 1 evidence
Alitretinoin
The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Alitretinoin.
Level 2 evidence
Alogliptin
The therapeutic efficacy of Alogliptin can be decreased when used in combination with Levonorgestrel.
Level 2 evidence
Alpelisib
The metabolism of Levonorgestrel can be increased when combined with Alpelisib.
Level 2 evidence
Alteplase
The risk or severity of adverse effects can be increased when Levonorgestrel is combined with Alteplase.
Level 1 evidence
Amobarbital
The metabolism of Levonorgestrel can be increased when combined with Amobarbital.
Level 1 evidence
Enter your NPI to unlock 9 major interactions for Skyla
Skyla (Levonorgestrel) has 477 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Skyla (Levonorgestrel) has 57 major, 295 moderate, and 125 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Skyla. Always confirm against the full prescribing information.