Tizanidine Hydrochloride Drug Interactions: 128 Major
Tizanidine Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tizanidine Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abacavir
Tizanidine may increase the hepatotoxic activities of Abacavir.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Tizanidine.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Tizanidine is combined with Acetazolamide.
Level 2 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Tizanidine.
Level 2 evidence
Acyclovir
The metabolism of Acyclovir can be decreased when combined with Tizanidine.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Tizanidine is combined with Alfentanil.
Level 2 evidence
Alfuzosin
The therapeutic efficacy of Tizanidine can be decreased when used in combination with Alfuzosin.
Level 2 evidence
Allopurinol
The serum concentration of Tizanidine can be increased when it is combined with Allopurinol.
Level 1 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Tizanidine is combined with Almotriptan.
Level 2 evidence
Alosetron
The serum concentration of Tizanidine can be increased when it is combined with Alosetron.
Level 1 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Tizanidine.
Level 2 evidence
Aminosalicylic acid
Aminosalicylic acid may increase the hepatotoxic activities of Tizanidine.
Level 2 evidence
Enter your NPI to unlock 17 major interactions for Tizanidine Hydrochloride
Tizanidine Hydrochloride has 990 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Tizanidine Hydrochloride has 128 major, 486 moderate, and 376 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tizanidine Hydrochloride. Always confirm against the full prescribing information.