Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Vitrakvi. Always confirm against the full prescribing information.
100 interactions
Acetaminophen
The serum concentration of Acetaminophen can be increased when it is combined with Larotrectinib.
Level 2 evidence
Apalutamide
The serum concentration of Larotrectinib can be decreased when it is combined with Apalutamide.
Level 1 evidence
Aprepitant
The metabolism of Larotrectinib can be decreased when combined with Aprepitant.
Level 2 evidence
Articaine
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Articaine.
Level 1 evidence
Avanafil
The serum concentration of Avanafil can be increased when it is combined with Larotrectinib.
Level 1 evidence
Benzocaine
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Benzocaine.
Level 1 evidence
Benzyl alcohol
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Benzyl alcohol.
Level 1 evidence
Berotralstat
The metabolism of Larotrectinib can be decreased when combined with Berotralstat.
Level 2 evidence
Bupivacaine
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Bupivacaine.
Level 1 evidence
Butamben
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Butamben.
Level 1 evidence
Capsaicin
The risk or severity of methemoglobinemia can be increased when Larotrectinib is combined with Capsaicin.
Level 1 evidence
Cenobamate
The serum concentration of Larotrectinib can be decreased when it is combined with Cenobamate.
Level 1 evidence
Enter your NPI to unlock 33 major interactions for Vitrakvi
Vitrakvi (Larotrectinib) has 134 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Vitrakvi (Larotrectinib) has 39 major, 87 moderate, and 8 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Vitrakvi. Always confirm against the full prescribing information.