Wakix (Pitolisant Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Wakix. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Pitolisant can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
The serum concentration of Abemaciclib can be decreased when it is combined with Pitolisant.
Level 1 evidence
Abiraterone
The serum concentration of Abiraterone can be decreased when it is combined with Pitolisant.
Level 1 evidence
Acalabrutinib
The serum concentration of Acalabrutinib can be decreased when it is combined with Pitolisant.
Level 1 evidence
Acebutolol
Acebutolol may increase the QTc-prolonging activities of Pitolisant.
Level 1 evidence
Aceclofenac
The risk or severity of adverse effects can be increased when Aceclofenac is combined with Pitolisant.
Level 1 evidence
Acenocoumarol
The serum concentration of Acenocoumarol can be decreased when it is combined with Pitolisant.
Level 1 evidence
Acetaminophen
The serum concentration of Acetaminophen can be decreased when it is combined with Pitolisant.
Level 1 evidence
Acetylcholine
The risk or severity of adverse effects can be increased when Pitolisant is combined with Acetylcholine.
Level 2 evidence
Acetylsalicylic acid
The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Pitolisant.
Level 1 evidence
Acyclovir
The metabolism of Acyclovir can be increased when combined with Pitolisant.
Level 2 evidence
Adagrasib
The serum concentration of Adagrasib can be decreased when it is combined with Pitolisant.
Level 1 evidence
Enter your NPI to unlock 9 major interactions for Wakix
Wakix (Pitolisant Hydrochloride) has 1140 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Wakix (Pitolisant Hydrochloride) has 69 major, 780 moderate, and 291 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Wakix. Always confirm against the full prescribing information.