Xenical (Orlistat) Drug Interactions: 1 Major, 214 Moderate
Xenical (Orlistat) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xenical. Always confirm against the full prescribing information.
100 interactions
Abacavir
Abacavir may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
Abiraterone
Orlistat may increase the hepatotoxic activities of Abiraterone.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
Acenocoumarol
Orlistat may increase the anticoagulant activities of Acenocoumarol.
Level 1 evidence
Acetaminophen
Acetaminophen may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
Acetazolamide
Orlistat can cause a decrease in the absorption of Acetazolamide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
Albendazole
Albendazole may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
Alitretinoin
Orlistat can cause a decrease in the absorption of Alitretinoin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Allopurinol
Allopurinol may increase the hepatotoxic activities of Orlistat.
Level 2 evidence
alpha-Tocopherol acetate
Orlistat can cause a decrease in the absorption of alpha-Tocopherol acetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
alpha-Tocopherol succinate
Orlistat can cause a decrease in the absorption of alpha-Tocopherol succinate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Xenical (Orlistat) has 541 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Xenical (Orlistat) has 1 major, 214 moderate, and 326 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xenical. Always confirm against the full prescribing information.